Twin explosions strike southern Syrian city

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BEIRUT (AP) — Syria‘s state-run news agency says two large explosions have struck the southern city of Daraa, causing multiple casualties and heavy material damage.


SANA did not immediately give further information or say what the target of Saturday’s explosions was.













The Britain-based Syrian Observatory for Human Rights says the blasts went off near a branch of the country’s Military Intelligence in Daraa.


The Observatory, which relies on a network of activists on the ground, says the explosions were followed by clashes between regime forces and rebels fighting to topple President Bashar Assad.


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Google says multiple services blocked in China

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SAN FRANCISCO (Reuters) – Google Inc said several of its online services have been blocked in China.


Traffic to Google’s services in China dropped sharply beginning Friday evening there, according to an online “Transparency Report” website operated by Google, which provides updates about access to its services in different parts of the world.













Among the sites affected were Google’s search engine and its Gmail web email product.


The disruptions come as China’s once-in-a-decade meeting to appoint new leadership gets underway.


A Google spokeswoman said the company did not know why the disruption was happening. Google said in a statement that it had “checked and there’s nothing wrong on our end.”


Google’s YouTube video service has been inaccessible in China since 2009, while access to other services in China are blocked sporadically.


In 2010 Google relocated its Chinese search engine to Hong Kong after a spat with authorities over censorship and cyber-attacks that Google said originated in China.


(Reporting By Alexei Oreskovic; editing by John Wallace)


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“Hunger Games” star Jennifer Lawrence will not diet for role

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LOS ANGELES (Reuters) – “The Hunger Games” star Jennifer Lawrence will not be dieting for a role any time soon.


Lawrence, 22, who plays the famished Katniss Everdeen in the life-or-death thriller series, told Elle magazine in an interview to be published on November 13 that dropping a few pounds will not be part of her script.













“I’m never going to starve myself for a part,” Lawrence said, a view out of step with many in diet-obsessed Hollywood.


Lawrence’s figure in “The Hunger Games” raised eyebrows of some critics, who believed the actress looked a little too healthy for a character struggling to eat.


“I don’t want little girls to be like, ‘Oh, I want to look like Katniss, so I’m going to skip dinner,” Lawrence said. “That’s something I was really conscious of during training…I was trying to get my body to look fit and strong – not thin and underfed.”


Suffering for a role by rapidly losing or gaining weight is part of Hollywood lore.


Natalie Portman was applauded for dropping some 20 pounds for her Oscar-winning role as a ballerina in 2010′s “Black Swan”. Likewise Robert De Niro nabbed an Oscar after packing on 60 extra pounds in 1980 boxing film “Raging Bull”.


Lawrence’s figure did not hurt the first installment of the “The Hunger Games” series, which was released in March and has grossed some $ 670 million worldwide. The actress has signed on for three sequels.


(Reporting By Jill Serjeant; Editing by David Gregorio)


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Nutella maker says will brave French tax hike

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PARIS (Reuters) – The makers of the renowned Nutella food spread say they will not change the lucrative recipe even if France, its biggest market, endorses proposals to quadruple tax on a key ingredient of the gooey mix, palm oil.


Senators in France, where a left-wing government is hiking tax generally to help slash a bloated debt, have proposed a 300 percent tax hike on palm oil on the grounds that its production harms the environment and its consumption fuels obesity.













Frederic Thil, French director for Ferrero, the Italian firm that makes the sugary, chocolate-colored paste, sounded a defiant note in Le Parisien daily.


“The arguments are unfair and the repercussions would be catastrophic,” he told the newspaper.


More than 100 million jars of Nutella were sold in France alone in 2008, according to Ferrero, whose website says the recipe sold in large quantities across the Western world was invented in the backroom of an Italian pastry shop in 1944.


The main ingredients are sugar, milk powder, hazelnuts, cocoa, emulsifier, flavoring and palm oil, on which a tax of almost 100 euros per metric tonne is levied in France at the moment.


That tax would rise to 400 euros a tonne if the proposal floated by a Senate committee earlier this month secures majority backing in the Senate and in the lower house of parliament, the National Assembly.


France, which is keen to find other funding sources for a generous healthcare system in cash-strapped times, has already raised tax on sugary drinks and recently hatched plans to hike tax on beer to help plug the hole in public welfare finances.


Thil said the maker of Nutella, popular in many countries as a breakfast fare smeared onto slices of bread, would do all it could to limit the hit from any tax rise for consumers.


Palm oil, also extensively used in margarine, biscuits and crisps, makes up about 20 percent of the Nutella mix. The 300 percent tax rise, if passed on, would raise the cost of a 1-kilo jar or the spread by 0.06 euros, according to ASEF, an association of doctors that backs the tax hike proposal.


The other argument made for a tax increase is that it will encourage a shift away from intensive production methods that have prompted destruction of forests in countries such as Malaysia, a major exporter of palm oil.


(Reporting By Brian Love; Editing by Toby Chopra)


Health News Headlines – Yahoo! News



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Four days later, Obama wins Florida

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ST. PETERSBURG, Fla. - President Barack Obama was declared the winner of Florida's 29 electoral votes Saturday, ending a four-day count with a razor-thin margin that narrowly avoided an automatic recount that would have brought back memories of 2000.


No matter the outcome, Obama had already clinched re-election and now has 332 electoral votes to Romney's 206.


The Florida Secretary of State's Office said that with almost 100 per cent of the vote counted, Obama led Republican challenger Mitt Romney 50 per cent to 49.1 per cent, a difference of about 74,000 votes. That was over the half-per cent margin where a computer recount would have been automatically ordered unless Romney had waived it.


There is a Nov. 16 deadline for overseas and military ballots, but under Florida law, recounts are based on Saturday's results. Only a handful of overseas and military ballots are believed to remain outstanding.


It's normal for election supervisors in Florida and other states to spend days after any election counting absentee, provisional, military and overseas ballots. Usually, though, the election has already been called on election night or soon after because the winner's margin is beyond reach.


But on election night this year, it was difficult for officials — and the media — to call the presidential race here, in part because the margin was so close and the voting stretched into the evening.


In Miami-Dade, for instance, so many people were in line at 7 p.m. in certain precincts that some people didn't vote until after midnight.


The hours-long wait at the polls in some areas, a lengthy ballot and the fact that Gov. Rick Scott refused to extend early voting hours has led some to criticize Florida's voting process. Some officials have vowed to investigate why there were problems at the polls and how that led to a lengthy vote count.


If there had been a recount, it would not be as difficult as the lengthy one in 2000. The state no longer uses punch-card ballots, which became known for their hanging chads. All 67 counties now use optical scan ballots where voters mark their selections manually.


Republican George W. Bush won the 2000 contest after the Supreme Court declared him the winner over Democrat Al Gore by a scant 537 votes.


The win gave Obama victories in eight of the nine swing states, losing only North Carolina. In addition to Florida, he won Ohio, Iowa, New Hampshire, Wisconsin, Virginia, Colorado and Nevada.

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Assad says will live and die in Syria

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DOHA (Reuters) – President Bashar al-Assad said he would “live and die” in Syria and warned that any Western invasion to topple him would have catastrophic consequences for the Middle East and beyond.


Assad’s defiant remarks coincided with a landmark meeting in Qatar on Thursday of Syria’s fractious opposition to hammer out an agreement on a new umbrella body uniting rebel groups inside and outside Syria, amid growing international pressure to put their house in order and prepare for a post-Assad transition.













The Syrian leader, battling a 19-month old uprising against his rule, appeared to reject an idea floated by British Prime Minister David Cameron on Tuesday that a safe exit and foreign exile for the London-educated Assad could end the civil war.


“I am not a puppet. I was not made by the West to go to the West or to any other country,” he told Russia Today television in an interview to be broadcast on Friday. “I am Syrian; I was made in Syria. I have to live in Syria and die in Syria.”


Russia Today’s web site, which published a transcript of the interview conducted in English, showed footage of Assad speaking to journalists and walking down stairs outside a white villa. It was not clear when he had made his comments.


The United States and its allies want the Syrian leader out, but have held back from arming his opponents or enforcing a no-fly zone, let alone invading. Russia has stood by Assad.


The president said he doubted the West would risk the global cost of intervening in Syria, whose conflict has already added to instability in the Middle East and killed some 38,000 people.


“I think that the price of this invasion, if it happened, is going to be bigger than the whole world can afford … It will have a domino effect that will affect the world from the Atlantic to the Pacific,” the 47-year-old president said.


“I do not think the West is going in this direction, but if they do so, nobody can tell what is next.”


QATAR, TURKEY CHIDE OPPOSITION


Backed by Washington, the Doha talks underline Qatar’s central role in the effort to end Assad‘s rule as the Gulf state, which funded the Libyan revolt to oust Muammar Gaddafi, tries to position itself as a player in a post-Assad Syria.


Qatari Prime Minister Hamad bin Jassim Al Thani urged the Syrian opposition to set its personal disputes aside and unite, according to a source inside the closed-door session.


“Come on, get a move on in order to win recognition from the international community,” the source quoted him as saying.


Turkish Foreign Minister Ahmed Davutoglu delivered a similar message, saying, according to the source: “We want one spokesman not many. We need efficient counterparts, it is time to unite.”


An official text of a speech by Qatari Foreign Minister Khalid Mohamed al-Attiyah showed he told the gathering: “The Syrian people awaits unity from you, not divisions … Your agreement today will prove to the international community that there is a unity … and this will reflect positively in the international community’s stance towards your fair cause.”


Across Syria, more than 90 people were killed in fighting on Thursday, the Syrian Observatory for Human Rights said.


In Turkey’s Hatay border province, two civilians, a woman and a young man, were wounded by stray bullets fired from Syria, according to a Turkish official. Turkish forces increased their presence along the frontier, where officials have said they might seek NATO deployment of ground to air missiles.


Syria poses one of the toughest foreign policy challenges for U.S. President Barack Obama as he starts his second term.


International rivalries have complicated mediation efforts. Russia and China have vetoed three Western-backed U.N. Security Council resolutions that would have put Assad under pressure.


Syria’s conflict, pitting mostly Sunni Muslim rebels against forces dominated by Assad’s Alawite minority, whose origins lie in Shi’ite Islam, has fuelled sectarian tensions across the Middle East. Sunni Arab countries and Turkey favor the rebels, while Shi’ite Iran backs Assad, its main Arab ally.


“VICIOUS CIRCLE”


The main opposition body, the Syrian National Council (SNC), has been heavily criticized by Western and Arab backers of the revolt as ineffective, run by exiles out of touch with events in Syria, and under the sway of the Islamist Muslim Brotherhood.


British Foreign Minister William Hague said London would now talk to rebel groups inside Syria, after U.S. Secretary of State Hillary Clinton last week criticized the SNC and called for a new opposition body to include those “fighting and dying”.


But the plan for a body that could eventually be considered a government-in-waiting capable of winning foreign recognition and therefore more military backing ran into trouble almost as soon as it was proposed by SNC member Riyad Seif.


The meeting has so far been bogged down by arguments over the SNC representation and the number of seats the rival groups – which include Islamists, leftists and secularists – will have in a proposed assembly. Seif said he hoped for agreement on that on Thursday night, although the talks may continue into Friday.


Senior SNC member Burhan Ghalioun said the participants were moving towards consensus: “The atmosphere was positive. We all agree that we don’t want to walk away from this meeting in failure,” he told reporters.


Seif’s proposal is the first concerted attempt to merge opposition forces to help end the devastating conflict.


The initiative would also create a Supreme Military Council, a Judicial Committee and a transitional government-in-waiting of technocrats – along the lines of Libya’s Transitional National Council, which managed to galvanize international support for its successful battle to topple Gaddafi.


Michael Doran of the Brookings Institute in Washington told a forum in Doha it would not work for Syria. “It’s not a ridiculous idea, but it’s not going to succeed,” he said.


A diplomat on the sidelines of the talks said international divisions in the U.N. Security council did not help.


“It’s a vicious circle. They are asking the opposition to unite when they admit they are not themselves united,” he said.


(Writing by Tom Perry and Samia Nakhoul; Editing by Alistair Lyon, Alastair Macdonald and Philippa Fletcher)


World News Headlines – Yahoo! News



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Social media shakes up solitary online FX trading

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LONDON (Reuters) – The solitary world of online foreign exchange trading is emerging from the shadows as solo investors turn to specialist social media networks to link up with their peers and seek market-beating strategies.


Individual or retail trading, estimated at 8-10 percent of the $ 2.5 trillion daily spot FX market, used to conjure an image of a lone trader with little contact with the outside world.













But that is changing. Thanks to specially tailored websites known as social trading networks, users are able to see and even copy the trades of top-ranked rivals, swap ideas and gauge the market mood in online chat with a community of contacts.


“In the world of trading there are a lot of signals but social media gives us the market sentiment and it is ideal for chatting to people across the world for trade ideas,” said Patrick Orini, who has been trading FX online since 2004.


Retail forex traders make their deals using personal accounts through brokers such as Alpari, FxPro and IronFX. Increasingly, traders are hooking up their broker accounts with social trading networks, such as eToro, Currensee and Tradeo.


Traders usually pay a subscription to use the service while the social network and the broker might share revenue on trades.


In a system reminiscent of microblog network Twitter, top players who make their trades visible can gather thousands of followers, some of whom pay to copy their strategies.


Orini’s trading account on a social trading network called Tradeo has 500 followers, of whom around 20 copy his trades.


If online investors do well in their trades, they will attract more followers and will be ranked higher on the trader “leaderboard” posted on the site.


Retail FX has grown over the last decade as brokers allow individual traders to take highly leveraged positions previously accessible only to institutional investors. The largest group of market players is based in Japan.


eToro, one the world’s largest social trading platforms has processed more than 20 million trades since it went live at the beginning of 2012.


Tradeo, a social network for forex traders based in Tel Aviv, launched three months ago and, according to its co-founder and CEO Jonathan Adest, the site has posted up to half a billion dollars of trades from around 10,000 traders since then.


“It’s not a broker, but a network for brokers — a bit like an online trading room,” Adest said.


He said Tradeo also combats a key hazard of online trading — inaccurate or bogus information. Traders often swap ideas on comment boards, but anonymity and low security makes it difficult to weed out spam.


“The idea of creating a niche social network for forex traders is to help verify commentators usually found in chat rooms and comment boards,” Adest said.


In its increased use of social media, online forex trading is catching up with developments in the equities market.


Retail equities trading is estimated to account for up to half of trade in UK small companies. Retail FX’s smaller share of the overall market reflects the fact that most trade is over-the-counter and lack of volatility that make it harder to turn a profit.


TWITTER


In the equities market, analysis of Twitter postings and news headlines has been used to predict stock price movements.


London-based hedge fund firm Derwent Capital is launching a new spread betting application for retail traders in January that will use Twitter’s 350 million daily tweets to create a sentiment indicator covering currency pairs and other assets.


Social media makes existing currency market sentiment models more effective, said John Hardy, head of FX strategy at Saxo Bank.


“It would be a new way to measure “sentiment” in real time, something that banks can do already via how people are actually trading…but the Twitter measures might be able to bring new nuances and sophistication,” he said.


Arguably, solo traders who hook up to social trading networks are seeking an edge in the “wisdom of crowds”.


“The reason why so many people, like myself, do share their activity and ideas is to help each other and build the community,” Orini said. “I got so many valuable ideas from other traders, that I’m more than happy to share my ideas as well.”


(Editing by Nigel Stephenson)


Internet News Headlines – Yahoo! News



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Andy Summers film documents surviving the Police

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LOS ANGELES (Reuters) – Police guitarist Andy Summers has always been a multifaceted artist – musician, songwriter, photographer and author. Now he can add filmmaker to his extensive resume.


“Can’t Stand Losing You: Surviving the Police,” Summers’ 90-minute documentary film that chronicles his musical career and life with supergroup, has its world premiere at the DOC NYC festival in New York on Friday.













Summers, who narrates the film, describes it as “a musical journey” that uses live footage from the 2007-2008 Police reunion world tour, along with lots of archival material from both the early Police days and the London punk scene.


“But it’s not done as a chronological story,” he told Reuters. “We establish the fact we’re doing the reunion tour early on, and then it dips in and out of live Police concert footage, and then starts going back to the earlier days.”


Based on his 2006 memoir “One Train Later,” the documentary also incorporates rare footage dating back to the 1960s, when Summers, now 69, was involved with the early British rock scene and seminal artists including British vocalist and keyboard player Zoot Money and Eric Burdon. The film also features many still photographs that the rock star took along the way.


“I was always interested in photography, so it was very natural for me to document everything, whether it was backstage at some grungy club or on early tours with the Police,” he said.


“So there’s a lot of intimate moments and interesting shots and archival stuff, especially in the first 25 minutes of the film, with the Sex Pistols appearing and so on.”


BUMPING INTO FAME


Following his book’s lead, the film also documents the serendipitous nature of the formation of the Police, one of the biggest bands in rock history, when Summers “just happened to bump into” drummer Stewart Copeland in a London Underground station one day in 1977.


The two decided to have coffee and discuss forming a new band with a then-unknown singer called Sting, whom they had just met.


“One train later, and it all might never have happened,” recalled Summers, “which is why I titled the book ‘One Train Later.’”


He would have preferred that title for the documentary. “It’s much hipper and doesn’t pander to the obvious Police connection,” he said, “so I’m hoping at some point we’ll change it to that.”


Inevitably, the film also focuses on the breakup of the always-combustible and often acrimonious trio.


“It’s obviously a very painful and poignant moment, when we all realize, ‘Well, that’s it,’” Summers said of the 2008 footage documenting the band’s final dissolution.


“The camera lingers on all our faces, and you can see the raw emotion there. It’s very bittersweet.”


As for rumors that the Police may re-form yet again for another tour, Summers does not think that is likely, even though their 30th reunion tour grossed more than $ 350 million.


“But then I never thought we’d get back together to do the last tour, so I never shut the door on anything,” he said. “I personally think that my book was somewhat of a provoking agent in getting the Police reunited, so maybe this film will do the same thing again.”


(Reporting by Iain Blair, Editing by Jill Serjeant, Patricia Reaney and Lisa Von Ahn)


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Setback for first malaria vaccine in African trial

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LONDON (Reuters) – The world’s first potential malaria vaccine proved only 30 percent effective in African babies in a crucial trial, calling into question whether it can be a useful weapon in the fight against the deadly disease.


The surprisingly poor result for the vaccine, which GlaxoSmithKline has been developing for three decades, leaves several years of work ahead before a protective malaria shot could be ready for countries that desperately need one.













Malaria, a mosquito-borne parasitic disease, kills hundreds of thousands a year, mainly babies in Africa, and scientists say an effective vaccine is key to hopes to eradicate it.


Philanthropist Bill Gates, who helped fund the GSK vaccine’s development, said further research was now needed to see whether and how it might be used.


“The efficacy came back lower than we had hoped, but developing a vaccine against a parasite is a very hard thing to do,” he said in a statement.


Results from the final-stage trial with 6,537 babies aged six to 12 weeks showed the vaccine provided “modest protection”, reducing episodes of the disease by 30 percent compared to immunisation with a control vaccine, researchers said on Friday.


That efficacy rate a year after vaccination is less than half the 65 percent in an earlier trial in babies which analysed protection rates after six months. It is also a lot less than the 50 percent rate seen in five to 17 month-olds.


Vaccinating babies, rather than toddlers, is the preferred option, since the new vaccine could then be added to other routine infant immunisations. A separate programme for older children would involve a lot of extra costs.


Eleanor Riley, a professor of immunology at the London School of Hygiene and Tropical Medicine said the results showed that GSK’s vaccine, called RTS,S or Mosquirix, is potentially useful, but “not the complete solution”.


“The slightly lower than expected efficacy will … affect the cost-benefit analysis that health providers and funders will have to undertake before deciding whether the vaccine represents the best use of limited financial resources,” she said.


NOT GIVING UP


Despite the setback, Britain’s top drugmaker said it would push ahead with developing RTS,S and GSK Chief Executive Andrew Witty said it could be an important tool in fighting malaria.


“We’ve been at this for 30 years, and we’re certainly not going to give up now,” he told reporters on a conference call.


GSK does not expect to make any profit from the vaccine, which would only be sold in poor countries.


Witty reiterated a promise that if RTS,S is ultimately approved for market, it would be priced at cost of manufacture plus a 5 percent margin, and the margin would be reinvested by GSK in malaria research.


Given the target market, it is governments and international groups that will fund the vaccine’s roll-out, and they now need more positive data before deciding whether it is worth buying.


“We will have to have more information to give us a clearer idea as to how useful this vaccine will be,” said Seth Berkley, CEO of the GAVI Alliance, which funds bulk-buy vaccination programmes for poorer nations.


In particular, Berkley told Reuters he wanted to see longer-term data, including the effect of booster shots, and an analysis of how the vaccine performed in different settings.


Details of the malaria trial, which is Africa’s largest ever clinical trial involving almost 15,500 children in seven countries, were presented at a medical meeting in Cape Town and published online by the New England Journal of Medicine.


Witty said he would have liked to have seen efficacy rates of around 50 percent in infants, but stressed that more data would become available before the trial ends in 2014 which may throw more light on why rates of success are so variable.


“It may open up a more customised approach to how this potential vaccine gets used,” he said.


Malaria is caused by a parasite carried in the saliva of mosquitoes. It is endemic in more than 100 countries worldwide and infected around 216 million people in 2010, killing around 655,000 of them, according to the World Health Organisation.


Control measures such as insecticide-treated bed nets, indoor spraying and anti-malaria drugs have helped cut cases and deaths significantly in recent years, but scientists say it will take an effective vaccine and many more years work to wipe out malaria.


Scientists around the world are working on other potential malaria vaccines but RTS,S is by far the furthest ahead in development.


Medications/Drugs News Headlines – Yahoo! News



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Obama: U.S. voted for tax hikes on rich

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President Barack Obama makes remarks on the "fiscal cliff" in the East Room of the White House (Kevin Lamarque …Claiming a mandate from his election romp over Mitt Romney, President Barack Obama announced Friday that he had invited Congressional leaders to the White House next week for talks on how to steer the battered economy away from a "fiscal cliff." Obama said he was open to compromise with Republicans—but that any final deal needed to raise taxes on the richest Americans.


"This was a central question during the election," the president said in brief remarks in the East Room of the White House. "It was debated over and over again, and on Tuesday night we found out that a majority of Americans agree with my approach.


"Our job now is to get a majority in congress to reflect the will of the American people," Obama said. "I'm not wedded to every detail of my plan. I'm open to compromise. I'm open to new ideas. I'm committed to solving our fiscal challenges. But I refuse to accept any approach that isn't balanced."


The president, who did not take questions on Friday, campaigned in part on a plan that would extend most of the Bush-era tax cuts, but allow them to expire for individuals making more than $200,000 or families pulling in $250,000. Republicans have said they want to prolong all of those rate reductions.


Obama said, as he has all year, that this means both sides agree on extending the middle-class reductions—and that doing so should not require "long negotiations or drama. ... Let's extend the middle-class tax cuts right now. Let's do that right now." (Republicans have resisted; extending those rates would reduce the party's leverage on tax hikes affecting the wealthy).


Republican Speaker John Boehner, speaking shortly before the president's appearance, said he was looking to Obama "to lead" and that he had a short, "cordial" conversation with the president earlier this week about ways to avoid the so-called fiscal cliff.


"I think we both understand that trying to find a way to avert the fiscal cliff is important for this country," Boehner said. "And I'm hopeful that productive conversations can begin soon so we can forge an agreement that can pass the Congress."


Boehner reiterated his opposition to raising tax rates as part of that deal, even on high-income earners, and says he sees the negotiations as a way to overhaul the tax code and the way the federal government pays for entitlement programs like Social Security and Medicare. (Boehner's emphasis on tax rates suggests a possible opening for a compromise that focuses on raising revenue by closing loopholes, which is also a part of Obama's plan).


Obama said he was "encouraged" by the speaker's comments.


The so-called "fiscal cliff" refers to a series of tax increases and deep spending cuts scheduled to occur Jan. 1, 2013 if Obama and his Republican foes fail to reach a deal. They include the expiration of a payroll tax cut and the Bush-era reductions in tax rates, the end of some unemployment benefits, and draconian reductions in domestic and military spending triggered because of the failure of the Congressional "Super Committee" to find $1.2 trillion in deficit reduction over 10 years.


Just how bad would it be if the president and House Republicans held hands and took the country over the cliff, Thelma & Louise style (or maybe à la Homer Simpson)?


The non-partisan Congressional Budget Office, Washington's gold standard for such analysis, warned in a report released Thursday that the consequences could be dire, including a drop in Gross Domestic Product of 0.5 percent in 2013, and a rise in unemployment to 9.1 percent by the end of next year.


The CBO report also noted that extending Bush-era tax cuts for individuals making under $200,000 per year or families making below $250,000—while letting the reductions on higher-income Americans expire—would boost the economy by 1 ¼ percent by the end of 2013. This reflects Obama's preferred course. Extending the tax cuts for the wealthiest Americans, noted the report, "would have a relatively small effect on output for dollar of budgetary cost."


"The American people understand that we're going to have differences and disagreements in the months to come. They get that," Obama said. "But on Tuesday, they said loud and clear that they won't tolerate dysfunction, they won't tolerate politicians who view compromise as a dirty word—not when so many Americans are still out of work."


"What the American people are looking for is cooperation, they're looking for consensus, they're looking for common sense. Most of all they want action," the president said. "I intend to deliver for them in my second term, and I expect to find willing partners in both parties to make that happen.


"So let's get to work."


Chris Moody contributed to this report.


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Ghana building collapse traps dozens, kills 1

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ACCRA, Ghana (AP) — A five-story shopping center built earlier this year in a bustling suburb of Ghana‘s capital collapsed Wednesday, killing at least one person and leaving several dozen people trapped in the rubble, authorities and eyewitnesses said.


Rescue crews used cranes to try and remove debris from the top of the building amid fears that machinery sifting through the wreckage could injure trapped survivors. Crowds of bystanders gathered as rescuers sifted through cement and glass.













The fatality at the Melcom Shopping Center at Achimota, a suburb of Accra, was confirmed by Public Affairs Officer of the Ghana Fire Service Billy Anaglate. “We are still working to find out the fate of others who may be trapped under,” he said.


Other officials told The Associated Press that the death toll was likely to rise.


An AP reporter at the scene saw at least one man pulled from the debris, covered in dust and who was then whisked into an ambulance.


A Greater Accra Regional Public Affairs officer, deputy superintendent Freeman Tettey, confirmed that one person died and told the AP that 51 have been rescued and sent to hospitals around the capital.


“I was on my way to the shop when l saw it crumpling down,” Kojo Boadi, an eyewitness, said.


President John Mahama declared the scene a disaster zone and cut short his election campaign in the north of the country to be able to visit the site. The presidential election is scheduled for December.


The five-story store opened in February is part of the Melcom chain owned by Indian immigrant magnate, Bhagwan Khubchandani. His late father arrived in Ghana in 1929 as a 14-year-old to work as a store boy in the-then Gold Coast.


The store sells a variety of cheap, imported household goods and appliances that are popular with working-class Ghanaians.


Africa News Headlines – Yahoo! News



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Exclusive: Google Ventures beefs up fund size to $300 million a year

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SAN FRANCISCO (Reuters) - Google will increase the cash it allocates to its venture-capital arm to up to $300 million a year from $200 million, catapulting Google Ventures into the top echelon of corporate venture-capital funds.


Access to that sizeable checkbook means Google Ventures will be able to invest in more later-stage financing rounds, which tend to be in the tens of millions of dollars or more per investor.


It puts the firm on the same footing as more established corporate venture funds such as Intel's Intel Capital, which typically invests $300-$500 million a year.


"It puts a lot more wood behind the arrow if we need it," said Bill Maris, managing partner of Google Ventures.


Part of the rationale behind the increase is that Google Ventures is a relatively young firm, founded in 2009. Some of the companies it backed two or three years ago are now at later stages, potentially requiring larger cash infusions to grow further.


Google Ventures has taken an eclectic approach, investing in a broad spectrum of companies ranging from medicine to clean power to coupon companies.


Every year, it typically funds 40-50 "seed-stage" deals where it invests $250,000 or less in a company, and perhaps around 15 deals where it invests up to $10 million, Maris said. It aims to complete one or two deals annually in the $20-$50 million range, Maris said.


LACKING SUPERSTARS


Some of its investments include Nest, a smart-thermostat company; Foundation Medicine, which applies genomic analysis to cancer care; Relay Rides, a carsharing service; and smart-grid company Silver Spring Networks. Last year, its portfolio company HomeAway raised $216 million in an initial public offering.


Still, Google Ventures lacks superstar companies such as microblogging service Twitter or online bulletin-board company Pinterest. The firm's recent hiring of high-profile entrepreneur Kevin Rose as a partner could help attract higher-profile deals.


Soon it could have even more cash to play around with. "Larry has repeatedly asked me: 'What do you think you could do with a billion a year?'" said Maris, referring to Google chief executive Larry Page.


(Editing by Muralikumar Anantharaman)


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Cancer trials can lack clear information on biopsies

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NEW YORK (Reuters Health) – People participating in cancer drug trials aren’t always given the most straightforward explanation of possible risks and benefits from invasive procedures that may be involved, according to a new study.


Biopsies of tumor tissue can help researchers figure out how well a test drug is working – but the invasive, sometimes painful procedures are typically of little benefit to study participants themselves.













The new findings show more than five percent of biopsies in such trials may result in complications, but that informed consent documents spend less time explaining those risks than they do for simple blood draws, which are much less invasive.


“Most of these procedures don’t have any therapeutic value for patients, they are burdensome, they’re painful and they carry risk,” said Jonathan Kimmelman, from the Biomedical Ethics Unit at McGill University in Montreal, Canada.


“Before you do a procedure like that on patients, you really want to have their adequate informed consent,” Kimmelman, who wasn’t involved in the new study, told Reuters Health.


“The only reason (patients) should submit to them is to contribute to science in some way,” and not with the hope the biopsies will help them get better, he said.


For the new study, researchers from the University of Texas MD Anderson Cancer Center in Houston reviewed 57 cancer trials by their institution that involved tumor biopsies for study subjects and were conducted in 2005 through 2010.


In 38 of those trials, a biopsy was mandatory for all participants, often as a way for researchers to tell if the drug in question had worked as intended. In some other cases, biopsies were used as pre-study checks to see if patients had the right type of tumor for a certain targeted drug.


Lead author Dr. Michael Overman and his colleagues found almost all informed consent documents didn’t specifically address the research alternatives to biopsies or the lack of likely benefits for patients themselves. The average document had just 39 words addressing the potential risks from study biopsies, compared to 48 words for blood draws.


In those trials, 576 patients had a total of 745 tumor biopsies – including lung, liver and head and neck biopsies. Thirty-nine of those resulted in complications, such as lung air leaks and bleeding, and six in major complications requiring patients to be hospitalized or to get further surgery, according to findings published Monday in the Journal of Clinical Oncology.


Overman said one of the problems has been that until now, there hasn’t been enough available data for study investigators to give patients a reliable estimate of their chance of a biopsy-related complication.


“The informed consent documents that are used are not always as clear as they could be,” Kimmelman said.


He added that not all cancer studies requiring biopsies are of the highest quality. And some don’t make it into the published scientific literature, where they could potentially help determine if a drug is approved or could guide treatment decisions for future patients.


“I think a lot of patients understandably think that when they’re volunteering for these studies they’re giving tissue for what is cutting-edge science, and sometimes that’s true, but not always,” Kimmelman said.


Both researchers agreed that as more targeted drugs are designed for patients with very specific types of cancer, research biopsies will become increasingly necessary to determine how well those drugs are working on the tumor itself.


“I think giving biopsies is a good thing. I think you learn from it, but you need to do it in an honest fashion,” Overman told Reuters Health.


Especially in early drug studies, the patients involved typically have few established treatment options.


“This is where we should say (to patients), ‘This is an experimental therapy, an experimental biopsy, and you don’t have to do it,’” Overman said.


SOURCE: http://bitly.com/U9NXK1 Journal of Clinical Oncology, online November 5, 2012.


Diseases/Conditions News Headlines – Yahoo! News



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Loughner gets life for deadly Ariz. rampage

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TUCSON, Ariz. (AP) — The man who pleaded guilty to a deadly Arizona shooting rampage that wounded former U.S. Rep. Gabrielle Giffords was sentenced to life in prison Thursday.


U.S. District Judge Larry Burns sentenced 24-year-old Jared Lee Loughner for the January 2011 attack that left six people dead and Giffords and others wounded.


Loughner pleaded guilty to federal charges under an agreement that guarantees he will spend the rest of his life in prison without the possibility of parole.


The hearing marked the first time victims — including Giffords — could confront Loughner in court.


Her astronaut husband, Mark Kelly, did all the talking for her, as the couple looked at Loughner and told him how his deadly rampage at the former congresswoman's political meeting had upended her life.


"Her life has been forever changed. Plans she had for our family and her career have been immeasurably altered," Kelly said. "Every day is a continuous struggle to do those things she once was so good at."


Loughner showed no emotion, and looked at the other victims. His mother sobbed nearby.


"Mr. Loughner, you may have put a bullet through her head but you haven't put a dent in her spirit and her commitment to make the world a better place," Kelly said.


Giffords kissed Kelly when he was done. He grabbed her hand and they walked away, with her limping.


Earlier, Loughner told Burns that he will not be speaking at the hearing.


Loughner pleaded guilty three months ago to 19 federal charges under an agreement that guarantees he will spend the rest of his life in prison without the possibility of parole.


Both sides reached the deal after a judge declared that Loughner was able to understand the charges against him. After the shooting, he was diagnosed with schizophrenia and underwent forcible psychotropic drug treatments.


At the hearing, Loughner, who wore dress pants and a dark brown shirt with a tie, heard from his victims.


"We've been told about your demons, about the illness that skewed your thinking," said Susan Hileman, at times visibly shaking, to Loughner. "Your parents, your schools, your community, they all failed you.


"It's all true," Hileman said. "It's not enough."


"You pointed a weapon and shot me three times," she said, staring directly at Loughner. He looked back at her. "And now I walk out of this courtroom and into the rest of my life and I won't think of you again."


Some victims, including Giffords, welcomed the plea deal as a way to move on. It spared victims and their families from having to go through a potentially lengthy and traumatic trial and locks up the defendant for life.


Christina Pietz, the court-appointed psychologist who treated Loughner, had warned that although Loughner was competent to plead guilty, he remained severely mentally ill and his condition could deteriorate under the stress of a trial.


When Loughner first arrived at a Missouri prison facility for treatment, he was convinced Giffords was dead, even though he was shown a video of the shooting. He eventually realized she was alive after he was forcibly medicated.


It's unknown whether Pima County prosecutors, who have discretion on whether to seek the death penalty against Loughner, will file state charges against him. Stephanie Coronado, a spokeswoman for Pima County Attorney Barbara LaWall, said Wednesday that no decision had been made.


It's unclear where Loughner will be sent to serve his federal sentence. He could return to a prison medical facility like the one in Springfield, Mo., where he's been treated for more than a year. Or he could end up in a prison such as the federal lockup in Florence, Colo., that houses some of the country's most notorious criminals, including Oklahoma City bombing conspirator Terry Nichols and "Unabomber" Ted Kaczynski.

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Canada firms to capitalize on nuclear trade with India

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NEW DELHI (Reuters) – Canadian firms will be able to export uranium and nuclear reactors to India for the first time in almost four decades under an agreement between the two nations, their prime ministers said, but more work is needed to implement the deal.


Once implemented, the agreement will end a ban on nuclear cooperation Canada imposed in 1976 after India secretly exploded its first nuclear bomb in 1974, commonly called the “Smiling Buddha”, using material from a Canadian-built reactor in India.













“Being able to resolve these issues and move forward is, we believe, a really important economic opportunity for an important Canadian industry, part of the energy industry, that should pay dividends in terms of jobs and growth for Canadians down the road,” Canadian Prime Minister Stephen Harper said on Tuesday on a visit to New Delhi.


A negotiator with the Canadian Nuclear Safety Commission (CNSC), speaking on condition of anonymity because of the delicacy of the talks, said that what remained was a careful legal review of the language; translation into French and Hindi; and then a signing.


This is not expected to take very long, he said. The two sides have set up a joint committee to liaise on nuclear issues, but he said it would not be negotiating.


India aims to lift its nuclear capacity to 63,000 MW in the next 20 years by adding nearly 30 reactors. The country currently operates 20 mostly small reactors at six sites with a capacity of 4,780 MW, or 2 percent of its total power capacity, according to the Nuclear Power Corporation of India Limited.


Canada’s ambassador to India, Stewart Beck, said on Monday his country wanted to be able to track all nuclear material, but that India felt it only needed to report to the International Atomic Energy Agency (IAEA).


It was not clear who made concessions in the talks and how effective the safeguards would be to ensure that Canadian material did not get used again for making nuclear weapons.


However, the CNSC official said India would now be required to notify Canada of any transfers to a third country and trade could only go to facilities that are safeguarded by the IAEA.


PROBABLY BEATING AUSTRALIA


Harper said the CNSC had worked to “achieve all of our objectives in terms of non-proliferation”.


Canada is in a race against Australia, its strategic ally but a commercial rival in the uranium business. Australia is also trying to nail down safeguards under which it too could sell uranium to India.


“We are effectively ahead of the Australians,” the CNSC official said, noting however that Russia and Kazakhstan were already supplying into India.


Opening up the Indian market would be a big help to Canada’s Cameco Corp, which is the world’s largest publicly traded uranium producer but which recently cut its long-term output targets due to the Fukushima disaster.


“Anytime we can reduce the roadblocks to selling our product around the world is always helpful,” Cameco chief executive Tim Gitzel told Reuters in Canada. “It opens a new market for us with the appropriate safeguards in place. So this is good news.”


Another potential beneficiary is Canadian engineering firm SNC Lavalin Group Inc, which bought the government’s commercial nuclear division, which designed the Candu reactor that is in use in numerous countries.


“As far as the sales of reactors goes, we would normally now request that Canada be accorded the same treatment as the Russians, the French and the Americans and that a site be designated in India for the implementation of at least a twin- unit Candu nuclear power station,” SNC Lavalin International President Ronald Denom, part of Harper’s delegation in India, told Reuters.


He also said it should open up the market to service the existing reactors in India.


Harper also said Canada welcomed foreign investment, after the country temporarily blocked Malaysian state oil firm Petronas’ C$ 5.17 billion ($ 5.19 billion) bid for gas producer Progress Energy Resources on October 20.


Late on Friday, Canada extended to December 10 its review of a $ 15.1 billion bid made in July by China’s CNOOC Ltd for Canadian energy producer Nexen Inc.


“Those decisions have to be taken looking at the global evolving economy in which we operate,” Harper said.


($ 1 = C$ 0.9965)


(Additional reporting by Julie Gordon in Toronto; Additional writing by Frank Jack Daniel; Editing by Jonathan Thatcher and Michael Roddy)


Canada News Headlines – Yahoo! News



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Apple's shares slide 4 percent to five-month low

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A Minute With: Taylor Lautner finding new dawn after “Twilight”

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LOS ANGELES (Reuters) – As dusk sets on the “Twilight” saga with the final film, actor Taylor Lautner is looking at a new dawn for the next stage in his career.


Lautner, 20, shot to fame after being cast as werewolf Jacob Black in the “Twilight” films, entangled in a torrid love triangle with Kristen Stewart‘s Bella Swan and Robert Pattinson‘s vampire Edward Cullen. He became a household name and pin-up for his clean-cut good looks and shirtless scenes.













In “Breaking Dawn – Part 2,” out in U.S. theaters on November 16, Lautner’s character finds new love, albeit unusual, and indulges his comedic side as the story comes to an end.


Lautner spoke to Reuters about leaving Jacob and his cast mates behind, and why the final film may leave fans in tears.


Q: What’s different about Jacob in “Breaking Dawn – Part 2″?


A: “He’s always been so stressed and emotional and things aren’t going his way and there was a huge weight lifted off his shoulders in this one, huge. It was nice to play that side of Jacob where he could sit back and relax and have a smile on his face and crack a few funny jokes every now and then.”


Q: Jacob finds his soul mate in Bella and Edward’s daughter Renesmee from the moment she is born. Was it challenging to balance his affection for her without coming across creepy?


A: “It was a challenge, and it is so complicated, but really nobody understands it more than Stephenie Meyer who created it. I was picking her brain all day long about it. She basically told me over and over again, ‘Taylor, stop trying to overthink it, stop trying to take it different places … It’s a life-long bond between two people, that’s it.’ In the movie, (Renesmee) is 10 years old, it’s much more of a protector relationship right now, and of course the relationship will grow but we don’t explore that, but it was important for me to keep it simple.”


Q: What are you going to miss most about your character and the franchise?


A: “These characters have never stopped changing throughout the entire franchise, and that’s what I love about Jacob. Jacob himself has grown up so much and gone through so many hurdles and it was a fantastic character to play. For me, it’ll be tough to say goodbye to spending time with people that I love. We’ve grown so close over the past few years. Our relationships will go on past this but to not have that excuse to spend day after day together while filming or promoting will be different.”


Q: “Twilight” fans are not just interested in your characters, they’re also interested in your personal lives. The past summer has seen a lot of attention on Robert and Kristen’s relationship. How do you handle that level of scrutiny?


A: “It’s unlike anything else because when we do talk about the movies, 90 percent of the time people want to know more about ourselves than the characters and what’s going on. I guess that just comes with a fan base like this, it comes with the job and you try and not let it affect you too much, but I have no complaints … The scrutiny, is it unfortunate? Yeah, but you just got to make your way around it and think about things more.”


Q: Do you feel protective of your cast members?


A: “Yes, I definitely do, we’re so close by this point, I think that it’s hard not to.”


Q: What do you hope “Twilight” fans take away from “Breaking Dawn – Part 2″?


A: “I just hope they’re happy and they’re proud because we really do make these movies for them. They’re the reason we are able to make them, their support is unreal and we’re so proud of this last one. This last one specifically wraps it up so nicely, it’s an amazing movie. During the movie, it’ll keep you on the edge of your seat but by the end, I think more than a few of the fans will be in tears.”


Q: Post-Twilight, where do you want to take your career to, what roles would you like to explore? I hear you have a cameo in the comedy “Grown Ups 2″?


A: “It was great to do (comedy), just hop in and show a different side, do something fun and work with somebody like Adam (Sandler). But now I’m looking forward to doing something different from that. There are a few projects that I’m very excited about that are extremely challenging and dramatic and would be tough.”


(Reporting By Piya Sinha-Roy, editing by Jill Serjeant and Patricia Reaney)


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Obama win clears health law hurdle, challenges remain

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WASHINGTON (Reuters) – President Barack Obama‘s re-election eliminates the possibility of a wholesale repeal of his signature healthcare reform law, but leaves questions about how many of the changes will be implemented as the national focus shifts to tackling the U.S. debt and deficit.


The 2010 Patient Protection and Affordable Care Act, the biggest overhaul of the $ 2.8 trillion U.S. healthcare system since the 1960s, aims to extend health coverage to more than 30 million uninsured Americans beginning in January 2014.













Republican challenger Mitt Romney had vowed to repeal the law if elected, calling it a costly government expansion despite the fact that the reforms are based on healthcare legislation he signed as governor of Massachusetts.


“There’s sort of an immediate acceptance that this law will stay in place in some meaningful way,” said Chris Jennings, a top healthcare adviser to former Democratic President Bill Clinton. “It’s sort of like a big barrier has been removed.”


Shares in hospitals and insurers that cater to Medicaid, the government insurance for the poor, rose slightly on Wednesday as markets expected the reform laws to be enacted. But health insurers with large employer-based businesses were off slightly, as the health reform law sets limits on their profits and mandates on coverage.


Obama still faces challenges in Congress. Republicans who retained control of the House of Representatives are expected to press for healthcare reform concessions, including delaying and 7scaling back a planned expansion of Medicaid, during negotiations to cut the federal deficit later this month.


But Julie Barnes, director of healthcare policy at the Bipartisan Policy Center, said Tuesday’s victory should give the president added leverage to set the healthcare segment of any deficit-cutting compromise largely on his own terms.


“President Obama has the opportunity to make bold leadership moves toward a bipartisan compromise on healthcare and the economy,” she said. “He has the standing to demand that each party see the investment all Americans have in reforming our broken healthcare system.”


DID MEDICARE HELP OBAMA?


In a related issue, Obama’s staunch defense of Medicare, the healthcare program for the elderly and disabled, may have helped his re-election, giving him an edge in close states including Ohio, Pennsylvania, Iowa, New Hampshire and Nevada.


Obama and his allies vigorously attacked Romney’s plan to convert the popular program that provides guaranteed benefits to one that gives beneficiaries a fixed payment to help them purchase their own health coverage.


Polls show older Americans oppose the idea by margins of 2-to-1, though it was unclear to what extent that opposition translated into votes.


Major provisions of the Affordable Care Act call for cooperation from individual U.S. states, including an expansion of Medicaid and the introduction of subsidized health insurance exchanges for individuals to buy their own coverage.


Governors and legislatures in as many as a half-dozen Republican-majority states oppose those plans and can refuse to act on them.


Other states may be ill-prepared for implementation but could begin to take action now that repeal is no longer a threat. States have until November 16 to say whether they intend to set up their own exchanges. Most will need to partner with the federal government to have one ready by 2014.


Soon after Obama emerged the winner, reform advocates called on his administration to encourage state support for Medicaid by assuring governors and legislatures that $ 930 billion in federal funds for financing the expansion will be pumped into struggling state budgets.


“This guarantee is essential for governors as they decide whether their programs should cover more low-income adults. It is therefore crucial that upcoming federal budget decisions give governors clear assurances that this funding is stable and won’t be reduced,” said Ron Pollack of Families USA, a Medicaid advocacy group.


The healthcare law that Republicans deride as “Obamacare” has already survived repeated attacks and emerged mostly intact.


The Supreme Court upheld the reforms in a landmark June ruling, but empowered states to opt out of the planned Medicaid expansion without losing federal funding for current programs.


The reform law is still the subject of about two-dozen lawsuits seeking to overturn a requirement that church-affiliated institutions cover birth control for employees.


(Editing by Michele Gershberg, Marilyn Thompson and David Storey)


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Boehner, Reid in talks to avert 'fiscal cliff'

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WASHINGTON (Reuters) - Fresh off the election, the two top leaders of Congress began tentative discussions on Wednesday aimed at heading off potential economic disaster at year's end, when simultaneous tax increases and spending cuts threaten to throw the United States into a recession.


The leader of the Senate's Democratic majority, Harry Reid, said he had conferred Wednesday morning with his Republican counterpart in the U.S. House of Representatives, Speaker John Boehner, and both had agreed not to "draw any lines in the sand" for the time being.


At the same time, Reid stressed that Democrats were not likely to budge from their standard negotiating position, that tax increases should apply to the wealthy, not those in the middle class or below.


The re-election of President Barack Obama and Democratic gains in the U.S. Senate, Reid said, had validated the party's position on taxes.


"I'm willing to negotiate at any time on any issue ... I want to work together but I want everyone to understand you can't push us around," Reid said


Reid said it was his preference they reach agreement in the post-election session of Congress that begins next week on ways to avoid the so-called "fiscal cliff" - the combination of expiring tax cuts and automatic across-the-board reductions in federal spending due at year's end.


He said would prefer a solution in this year's so-called lame duck session rather than enact a temporary fix for the fiscal cliff and would push the issue into the newly elected Congress, which starts in January.


"I'm not for kicking the can down the road," he told reporters. "We need to solve it."


Boehner, will deliver a statement at 3:30 p.m. EST on Wednesday on the need for a bipartisan deal.


Boehner will make his case a day after American voters gave Obama a second term, but maintained a divided government, with Republicans still in control of the House and Democrats still holding the Senate.


Boehner will argue that Republicans and Democrats must "take steps together," a spokesman said in a press release.


(Reporting By Thomas Ferraro; Editing by Fred Barbash and Jackie Frank)


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Cautious reformers tipped for new China leadership

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BEIJING (Reuters) – China‘s ruling Communist Party will this month unveil its new top leadership team, expected to again be an all-male cast of politicians whose instincts are to move cautiously on reform.


Sources close to the leadership say 10 main candidates are vying for seven seats on the party’s next Politburo Standing Committee, the peak decision-making body which will steer the world’s second-largest economy for the next five years.













Only two candidates are considered certainties going into the party’s 18th congress, which starts on Thursday: leader-in-waiting Xi Jinping and his designated deputy, Li Keqiang, who are set to be installed as president and premier next March.


Of the remaining eight contenders, only one has the reputation as a political reformer and only one is a woman.


Following are short biographies of the candidates, including their reform credentials and possible portfolio responsibilities.


XI JINPING


REFORM CREDENTIALS: Considered a cautious reformer, having spent time in top positions in Fujian and Zhejiang provinces, both at the forefront of China‘s economic reforms.


Xi Jinping, 59, is China‘s vice president and President Hu Jintao’s anointed successor. He will take over as Communist Party boss at the congress and then as head of state in March.


Xi belongs to the party’s “princeling” generation, the offspring of communist revolutionaries. His father, former vice premier Xi Zhongxun, fought alongside Mao Zedong in the Chinese civil war. Xi watched his father purged and later, during the Cultural Revolution, spent years in the hardscrabble countryside before making his way to university and then to power.


Married to a famous singer, Xi has crafted a low-key and sometimes blunt political style. He has complained that officials’ speeches and writings are clogged with party jargon and has demanded more plain speaking.


Xi went to work in the poor northwest Chinese countryside as a “sent-down youth” during the chaos of the 1966-76 Cultural Revolution, and became a rural commune official. He went on to study chemical engineering at Tsinghua University in Beijing and later gained a doctorate in Marxist theory from Tsinghua.


A native of the poor, inland province of Shaanxi, Xi was promoted to governor of southeastern Fujian province in 1999 and became party boss in neighboring Zhejiang province in 2003.


In 2007, the tall, portly Xi secured the top job in China‘s commercial capital, Shanghai, when his predecessor was caught up in a huge corruption case. Later that year he was promoted to the party’s standing committee.


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LI KEQIANG


REFORM CREDENTIALS: Seen as another cautious reformer due to his relatively liberal university experiences.


Vice Premier Li Keqiang, 57, is the man tipped to be China‘s next premier, taking over from Wen Jiabao.


His ascent will mark an extraordinary rise for a man who as a youth was sent to toil in the countryside during Mao’s Cultural Revolution.


He was born in Anhui province in 1955, son of a local rural official. Li worked on a commune that was one of the first places to quietly revive private bonuses in farming in the late 1970s. By the time he left Anhui, Li was a Communist Party member and secretary of his production brigade.


He studied law at the elite Peking University, which was among the first Chinese schools to resume teaching law after the Cultural Revolution. He worked to master English and co-translated “The Due Process of Law” by Lord Denning, the famed English jurist.


In 1980, Li, then in the official student union, endorsed controversial campus elections. Party conservatives were aghast, but Li, already a prudent political player, stayed out of the controversial vote.


He climbed the party ranks and in 1983 joined the Communist Youth League’s central secretariat, headed then by Hu Jintao.


Li later served in challenging party chief posts in Liaoning, a frigid northeastern rustbelt province, and rural Henan province. He was named to the powerful nine-member standing committee in 2007.


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WANG QISHAN


REFORM CREDENTIALS: A financial reformer and problem solver with deep experience tackling tricky economic and political problems.


Wang Qishan, 64, is the most junior of four vice premiers and an ex-mayor of Beijing. But he has a keen grasp of complex economic issues and is the only likely member of the Standing Committee to have been chief executive of a corporation, leading the state-owned China Construction Bank from 1994 to 1997. As such, he may take a leading role in shaping economic policy, including trade and foreign investment.


Wang is an experienced negotiator who has led finance and trade negotiations as well as the Strategic and Economic Dialogue with the United States. He is a favorite of foreign investors and has long been seen as a problem solver, sorting out a debt crisis in Guangdong province where he was vice governor in the late 1990s and replacing the sacked Beijing mayor after a cover-up of the deadly SARS virus in 2003.


Wang is also a princeling, son-in-law of a former vice premier and ex-standing committee member, Yao Yilin. His possible portfolio could be chairman of the National People’s Congress (China’s rubber-stamp parliament), head of parliament’s advisory body, executive vice premier (responsible for economic issues) or the party’s top anti-corruption official.


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LIU YUNSHAN


REFORM CREDENTIALS: A conservative who has kept domestic media on a tight leash.


Liu Yunshan, 65, may take over the propaganda and ideology portfolio for the Standing Committee.


He has a background in media, once working as a reporter for state-run news agency Xinhua in Inner Mongolia, where he later served in party and propaganda roles before shifting to Beijing.


As minister of the party’s Propaganda Department since 2002, Liu has also sought to control China‘s Internet, which has more than 500 million users. He has been a member of the wider Politburo for two five-year terms ending this year.


Liu has not worked directly for the Communist Youth League, but is aligned to it through his lengthy career in an inland, poor province, long ties to the party’s propaganda system and close relationship with Hu Jintao.


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LI YUANCHAO


REFORM CREDENTIALS: A reformer who has courted foreign investment and studied in the United States.


Li Yuanchao, 61, oversees the appointment of senior party, government, military and state-owned enterprise officials as head of the party’s powerful organization department. On the Standing Committee, he could head the fight against corruption.


Li, whose father was a vice-mayor of Shanghai, has risen far since his parents were persecuted and he was a humble farm hand during the Cultural Revolution.


Politically astute, Li can navigate between interest groups, from Hu’s Youth League power base to the princelings.


As party chief in his native province, Jiangsu, from 2002 to 2007, Li oversaw a rapid rise in personal incomes and economic development, attracting foreign investment from global industrial leaders such as Ford, Samsung and Caterpillar.


He earned mathematics and economics degrees from two of China‘s best universities and a doctorate in law. He also spent time at Harvard University’s Kennedy School of Government in the United States.


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ZHANG DEJIANG


REFORM CREDENTIALS: A conservative trained in North Korea.


Zhang Dejiang, 65, saw his chances of promotion boosted this year when he was chosen to replace disgraced politician Bo Xilai as Chongqing party boss. He also serves as vice premier in charge of industry, though his record has been tarnished by the downfall of the railway minister last year for corruption.


Zhang is close to former president Jiang Zemin who still wields some influence. He studied economics at Kim Il-sung University in North Korea and is a native of northeast China.


On his watch as party chief of Guangdong, the southern province maintained its position as a powerhouse of China‘s economic growth, even as it struggled with energy shortages, corruption-fuelled unrest and the 2003 SARS epidemic.


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ZHANG GAOLI


REFORM CREDENTIALS: A financial reformer with experience in more developed parts of China.


Zhang Gaoli, 65, party chief of the northern port city of Tianjin and a Politburo member since 2007, is seen as a Jiang Zemin ally but also acceptable to President Hu, who has visited Tianjin three times since 2008. Zhang is an advocate of greater foreign investment and he introduced financial reforms in a bid to turn the city into a financial center in northern China.


He was sent to clean up Tianjin, which was hit by a string of corruption scandals implicating his predecessor and the former top adviser to the city’s lawmaking body. The adviser committed suicide shortly after Zhang’s arrival.


A native of southeastern Fujian province, Zhang trained as an economist. He also served as party chief and governor of eastern Shandong province and as Guangdong vice governor.


Zhang is low-key with a down-to-earth work style, and not much is known about his specific interests and aspirations. But with his leadership experience in more economically advanced cities and provinces, including party secretary of the showcase manufacturing and export-driven city of Shenzhen, he could be named executive vice premier.


- – - – -


WANG YANG


REFORM CREDENTIALS: Seen by many in the West as a beacon of political reform.


Wang Yang, 57, is party chief of the export dependent economic hub of Guangdong province. He was not included in a list of preferred Standing Committee candidates drawn up by Xi, Hu and Hu’s predecessor, Jiang Zemin, according to sources close to the leadership, but is firmly in the running.


Born into a poor rural family in eastern Anhui province, Wang dropped out of high school and went to work in a food factory at age 17 to help support his family after his father died. These experiences may have shaped his desire for more socially inclusive policies, including his “Happy Guangdong” model of development designed to improve quality of life.


Concerned about the social impact of three decades of blistering development, he lobbied for social and political reform. However, this approach has drawn criticism from party conservatives and Wang has more recently adopted the party’s more familiar method of control and punishment to keep order.


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YU ZHENGSHENG


REFORM CREDENTIALS: Relatively low-key but considered a cautious reformer.


Yu Zhengsheng, 67, is party boss in China‘s financial hub and most cosmopolitan city, Shanghai.


His impeccable Communist pedigree made him a rising star in the mid-1980s until his brother, an intelligence official, defected to the United States. His close ties with Deng Pufang, the eldest son of late paramount leader Deng Xiaoping, spared him the full political repercussions but he was taken off the fast track.


Yu bided his time in ministerial ranks until bouncing back, joining the Politburo in 2002. However, the princeling’s age would require him to retire in 2017 after one term.


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LIU YANDONG


REFORM CREDENTIALS: Uncertain.


Liu Yandong, who turns 67 this month, is the only woman given a serious chance to join the Standing Committee but is considered a dark horse. She is a princeling also tied to President Hu’s Youth League faction.


If promoted, she could head up parliament’s advisory body, but her age would also force her to retire after only one term.


Her bigger challenge is that no woman has made it into the Standing Committee since 1949. Not even Jiang Qing, the widow of late Chairman Mao Zedong, made it that far.


Liu, daughter of a former vice-minister of agriculture, is currently the only woman in the 25-member Politburo, a minority in China‘s male-dominated political culture. She has been on the wider Politburo since 2007 as one of five state councilors, a rank senior to a cabinet minister but junior to a vice-premier.


(Reporting by Terril Yue Jones, Ben Blanchard, Benjamin Kang Lim and Sui-Lee Wee in Beijing. Additional reporting by Chris Ip, Grace Li, Jean Lin, Young Wang, Alice Woodhouse and Julie Zhu; Editing by Raju Gopalakrishnan and Mark Bendeich)


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