With Teva at crossroads, new CEO set to unveil vision

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NEW YORK/TEL AVIV (Reuters) – Teva Pharmaceutical Industries‘ new Chief Executive Jeremy Levin has promised investors it will be a very different company going forward. Next week he has to prove it.


Levin’s ability to paint a bright future for the world’s biggest maker of generic drugs at a meeting with investors and analysts on December 11 in New York became a bit more difficult last week, when Teva issued a 2013 earnings forecast that fell short of Wall Street estimates.












Levin, a big pharma veteran, is expected to shift Teva’s focus to branded drugs even as its most important such product, top-selling multiple sclerosis treatment Copaxone, faces new competition and a 2015 patent expiration. Investors are also hoping for a meaningful boost to the annual dividend while new management works to jumpstart a stagnant share performance.


“I’ve made a lot of money in Teva and I’ve seen this company wither in front of my eyes,” said Dan Hunt, a co-portfolio manager for RCM Capital Management’s Wellness Fund. Hunt’s fund no longer includes Teva shares, but RCM has small Teva holdings.


“The most important signal (shareholders) need to hear on the record from Levin is ‘whatever it takes I will protect you’,” Hunt said, adding that Teva has not delivered for its shareholders in years.


Teva’s U.S. shares are up about 2 percent in 2012 after falling 22.6 percent in 2011. They are off 35 percent from a 2010 peak at about $ 64. Shareholders of smaller Teva rivals Watson Pharmaceuticals Inc and Mylan Inc have fared far better with Watson up about 45 percent this year and Mylan shares up about 27 percent over the same period.


Levin has taken some preemptive steps to placate investors ahead of the meeting by announcing that the company plans to cut $ 1.5 billion to $ 2 billion in costs over the next five years, streamline operations and discontinue some research programs.


Morgan Stanley estimated that Copaxone sales account for 58 percent of Teva’s projected 2013 earnings. Levin will have to reveal how he plans to make up for the anticipated decline in Copaxone revenue beyond cost-cutting efforts.


Generic drugs accounted for 56 percent of Teva’s revenue last year, but the company faces obstacles to generic growth in the United States, the world’s largest market.


Following a wave of major patent expirations, the number of multibillion-dollar drugs going generic will diminish after the next couple of years. And new generic drugs are facing competition sooner along with faster price declines. Generic drugs are also facing considerable price pressure in Europe.


SMALL ACQUISITIONS


South African-born Levin, a former senior vice president for strategy at Bristol-Myers Squibb Co, took over as CEO of Israel’s biggest company in May, replacing Shlomo Yanai.


In five years at the helm, Yanai engineered a number of large acquisitions, including last year’s $ 6.5 billion purchase of U.S. drugmaker Cephalon, which has been viewed by some analysts as a disappointment. The company last month took a $ 481 million impairment charge related to the Cephalon deal.


Levin last week signaled a desire for more targeted acquisitions focused on Teva’s core areas of expertise, such as central nervous system disorders and respiratory diseases.


He has begun to whittle away at non-core businesses, selling Teva’s U.S. animal health unit to Bayer for up to $ 145 million. Investors said Teva needs to improve production efficiency and downsize or close some of its plants.


Levin, who implemented at Bristol-Myers a series of deals and alliances with small and large companies, has been credited with helping to guide Bristol through its enormous patent cliff as the blood clot preventer Plavix, which had been the world’s second biggest selling prescription medicine, lost exclusivity.


“The key is smart deals and getting an estimate of what a reasonable growth rate is going forward,” said Robert Caravella, equity research analyst for Victory Capital Management, which holds about $ 9 million in Teva convertible bonds.


“The biggest issue is there’s not an understanding of where revenue and earnings are going to go and how we’re going to get to that point,” he said.


BIGGER DIVIDEND?


Shareholders would also like to see Teva raise its dividend, which provides only a 2.5 percent return on the stock, below the industry average of about 4 percent. Alternatively, the company may decide to increase shareholder returns by boosting its $ 3 billion share buyback.


Steven Tepper, an analyst at brokerage Harel Finance, said Levin must demonstrate how Teva can again become a growth company or that it will be a value investment going forward through a significant dividend increase. “This plan will have to convince investors it’s making that move,” Tepper said.


RCM Capital’s Hunt said Levin must present “a strong, formed, clear strategic vision” of where the company is headed.


The question is whether it will be enough to convince disenchanted investors such as Stewart Capital, which has more than $ 1 billion in assets under management but sold its Teva holdings shortly after Levin took over.


Matthew DiFilippo, chief portfolio strategist for Stewart, was skeptical that one individual could effect the change necessary to transform Teva back into an industry darling. “So while we recognized his talents, we also recognized the challenges they face and we sold,” he said.


A lot of money remains on the sidelines waiting for what Levin has to say, said Ori Hershkovitz, managing partner at Israel-based pharmaceutical hedge fund Sphera. Levin needs to say he is committed to replenishing Teva’s branded pipeline and will do whatever it takes to replace those lost sales by 2016, Hershkovitz said, and he must “make the market believe it”.


(Additional reporting by Steven Scheer in Jerusalem; Editing by Leslie Gevirtz)


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Dems call Republicans 'hostage takers' on debt talks

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Screen shot from GOPHostageTakers.com


House Democrats on Wednesday launched a new microsite, GOPHostageTakers.com, criticizing Republican leaders for not holding a vote to exclusively extend middle-income tax rates for another year as part of avoiding the so-called fiscal cliff.


Current tax rates for all income levels are set to automatically increase in 2013 unless Congress takes action this year. Most Republicans want to extend the current rates for all income levels, while Democrats want taxes to increase for households earning more than $250,000 annually.


The Democratic Congressional Campaign Committee launched the site as part of a larger messaging effort to goad Republicans into voting on a bill that excludes those earning more than $250,000 from the rate extension.


This week, House Minority Leader Nancy Pelosi, a California Democrat, submitted a "discharge petition" that would force a vote on a bill to extend rates only for middle-class taxpayers, but only if she can persuade 218 members of the Republican-led House to sign it. (Realistically, it's unlikely.) On the microsite, House Democrats list the names of some Republicans they consider "vulnerable" who have declined to sign Pelosi's petition.


Earlier this year, the Republican-led House approved a bill to extend tax rates for all income brackets while the Democrat-controlled Senate passed a measure that extends them for households under the $250,000 level.



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Officials: NATO to decide on missiles for Turkey

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BRUSSELS (AP) — NATO foreign ministers are expected to approve Turkey‘s request for Patriot anti-missile systems to bolster its defense against possible strikes from neighboring Syria.


NATO foreign ministers are meeting on Tuesday and Wednesday in Brussels. Parliaments in both nations must approve the deployment, which would also involve several hundred soldiers.












Ankara, which has been highly supportive of the Syrian opposition, wants the Patriots to defend against possible retaliatory attacks by Syrian missiles carrying chemical warheads. NATO leaders have repeatedly said they would provide any assistance Turkey needs.


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Longtime editor at DC’s Vertigo imprint leaving

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PHILADELPHIA (AP) — DC Entertainment says its executive editor and senior vice president of Vertigo — a groundbreaking imprint whose titles have included “Hellblazer,” ”DMZ” and “Sandman” — is leaving early next year.


Karen Berger will step down in March after nearly 20 years at the helm, saying in a statement released by DC late Monday that she is ready for a professional change.












During her tenure at Vertigo, the imprint saw a wide range of writers and artists — Neil Gaiman, Jill Thompson, Becky Cloonan and Brian Wood, among them — who produced titles beyond the traditional superhero and villain archetype.


Gerard Way of My Chemical Romance and writer of “The Umbrella Academy” tweeted that Berger gave “us weird kids in high school a Sub Pop Records for comics.”


___


Online:


http://www.vertigocomics.com


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Julie Bowen and the Danger of Allergies

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What are the odds a child will be exposed to two powerful allergens at the same time? It happened to ” Modern Family” actress Julie Bowen’s son. He was stung by a bee – at the same time he was eating a peanut butter sandwich.


The toddler immediately went into anaphylactic shock. His entire face swelled up, including his eyes and lips, and his breathing became labored.












“We took him to the ER, where he was treated with epinephrine, and ever since then we’ve been vigilant about keeping him safe,” the Emmy-winning Bowen told the Los Angeles Times.


Bowen told the paper she’s speaking about the experience publicly because one in 13 children have food allergies and she wants to educate parents about the dangers.


According to Dr. Brian Schroer, a pediatric allergist with the Cleveland Clinic in Ohio, childhood allergies can indeed be serious business. Parents need to know what to watch out for.


“When introducing a new food to a young child, especially a common allergen, watch closely for signs of distress,” he said.


The most common food allergy symptoms are itchiness in the mouth, a rash on the face, the body or both, coughing, wheezing and vomiting.


If a child’s allergy is severe, as in the case of Bowen’s son, there will also be facial swelling, difficulty breathing and low blood pressure. Schroer said the Bowens did the right thing by rushing their son to the emergency room.


“Parents can also give their kids some Benadryl to help symptoms but should still seek urgent care,” he said. “For a child really in distress, call 911.”


Children may not have a reaction the first time they’re exposed to an allergen. Initial reactions can range from mild to severe, with the most profound reactions generally triggered by peanuts, tree nuts and shellfish. Insect strings also tend to produce strong reactions. However, even a mild symptom like itchiness or a light skin rash can portend more serious reactions in the future.


At the first sign of any allergy symptoms, Schroer recommended checking in with a pediatrician or allergist.


“They can take a complete medical history and conduct simple skin challenge tests to determine the cause,” he said.”If there is an allergy, parents should work with their doctor to create a food allergy action plan.”


Once a plan is in place, make sure everyone who cares for your child, including teachers, babysitters and after-school providers, are familiar with it. Schroer said sometimes that means giving a stern lecture to well-meaning grandparents who may not quite believe the child has an issue until they see it for themselves. And any child who is at risk for anaphylaxis should carry an epi-pen and other medications at all times, including school, play dates and vacation.


Bowen hopes there won’t be any more “P Bee and J” situations for her son. But if there are, she said she’s prepared. As she told the L.A. Times, “It’s pretty straightforward. I don’t need to know everything that happens during an anaphylactic reaction; it’s enough for me to know as a parent that it can kill you.”


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Conservative Republicans booted from House budget panel

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WASHINGTON (Reuters) - Two of the most conservative Republicans in the House of Representatives have been kicked off the House Budget Committee, a rare move that could make it easier for the panel to advance a deal with Democrats to cut fiscal deficits.


Representatives Tim Huelskamp of Kansas and Justin Amash of Michigan - both favorites of the anti-tax Tea Party movement - are among those Republicans voting most often against House Speaker John Boehner.


Huelskamp and Amash, who both will begin second terms in the House next month, voted against last year's deal to raise the federal debt limit and staunchly oppose any tax increases. Boehner has now included new revenue in his latest offer to avert the "fiscal cliff" of year-end tax hikes and automatic spending cuts. Given their voting records, winning support from Huelskamp and Amash for such a compromise seemed an uphill battle.


Huelskamp released a statement saying the Republican leadership "might think they have silenced conservatives but removing me and others from key committees only confirms our conservative convictions.


"This is clearly a vindictive move and a sure sign that the GOP establishment cannot handle disagreement," he said.


Huelskamp and Amash had said that despite sweeping changes to the Medicare and Medicaid healthcare programs, committee chairman Paul Ryan's budget did not make deep enough cuts to entitlement programs and military spending.


Boehner spokesman Michael Steel declined to be specific on the reasons for their ouster by the House Republican Steering Committee, which occurred Monday in a closed-door meeting.


"The Steering Committee makes decisions based on a range of factors," Steel said.


Huelskamp said he was given "limited explanation" for his removal from the Budget Committee, a move he called "vindictive." A spokesman for Amash could not be immediately reached for comment.


Huelskamp and Amash cast the only House Budget Committee votes against Ryan's budget plan earlier this year.


While there is often wrangling over committee chairmanships just before a new Congress takes office, it is rare for rank-and-file committee members to be stripped of their assignments.


The 34-member Republican steering committee is headed by Boehner and includes members of House leadership, committee chairs and other lawmakers representing different regions of the country.


The same group last week recommended that Ryan, the conservative former Republican vice presidential candidate, be renewed as Budget Committee chairman.


(Editing by Bill Trott)



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Gunmen assassinate peasant leader in Paraguay

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ASUNCION, Paraguay (AP) — Gunmen murdered one of the surviving leaders of a peasant movement whose land dispute with a powerful politician prompted the end of Fernando Lugo‘s presidency last June.


Vidal Vega, 48, was hit four times early Saturday by bullets from a 12-gauge shotgun and a .38-caliber revolver fired by two unidentified men who sped away on a motorcycle, according to an official report prepared at the police headquarters in the provincial capital of Curuguaty.












A friend, Mario Espinola, told The Associated Press that Vega was shot down when he stepped outside to feed his farm animals.


Vega was among the public faces of a commission of landless peasants from the settlement of Yby Pyta, which means Red Dirt in their native Guarani language.


He had lobbied the government for many years to redistribute some of the ranchland that Colorado Party Sen. Blas Riquelme began occupying in the 1960s.


By last May, the peasants finally lost patience and moved onto the land. A firefight during their eviction on June 15 killed 11 peasants and six police officers, prompting the Colorado Party and other leading parties to vote Lugo out of office for allegedly mismanaging the dispute.


Twelve suspects, nearly all of them peasants from Yby Pyta, have been jailed without formal charges since then on suspicion of murdering the officers, seizing property and resisting authority. The prosecutor had six months to develop the case and will present his findings Dec. 16.


Vega was expected to be a witness at the criminal trial, since he was among the few leaders who weren’t killed in the clash or jailed afterward.


He wasn’t charged because he was away getting supplies when the violence erupted at the settlement erected by the peasants inside Riquelme’s ranch, the Naranjaty Commission’s secretary, Martina Paredes, told the AP.


“We think he was assassinated by hit men who were sent, we don’t know by whom, perhaps to frighten us and frustrate our fight to recover the state lands that were illegally taken by Riquelme,” she said.


Riquelme, who died of natural causes about a month after the battle in June, occupied the land during the dictatorship of Alfredo Stroessner, whose government gave away land for free to anyone willing to put it to productive use.


A local court in Curuguaty upheld Riquelme’s claim to the land years later. Lugo’s government later sought to overturn the decision, but the case remains tied up in court.


Latin America News Headlines – Yahoo! News


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A bachelorette no more: Ashley Herbert weds beau

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NEW YORK (AP) — Ashley Hebert (AY’-behr) is no longer a “Bachelorette.”


The 28-year-old Maine native got hitched over the weekend in Pasadena, Calif., to 35-year-old J.P. Rosenbaum of Long Island, who proposed to her on the seventh season of the ABC dating reality show “The Bachelorette.” Hebert tweeted that “12/1/12 goes down in history as the best day of my life!!”












Natalia Desrosiers, spokeswoman for Warner Bros. Television, which produces the show, said the wedding will be aired on Dec. 16 on ABC.


Hebert, who also competed on the 15th season of “The Bachelor,” grew up in Madawaska, Maine, and is a dentist. The couple now resides in the New York City area.


Only one other couple that met on the TV show has married. Bachelorette Trista Rehn married Vail, Colo., firefighter Ryan Sutter in 2003.


Entertainment News Headlines – Yahoo! News


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Estudio asocia método de relajación con la disminución de los sofocos

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NUEVA YORK (Reuters Health) – Aunque los estudios sobre los


efectos de las técnicas de relajación en los síntomas de la












menopausia dieron resultados contradictorios, un ensayo de


Suecia se define a favor del enfoque como una alternativa a la


terapia hormonal.


Un grupo de mujeres postmenopáusicas entrenadas para


relajarse antes y durante la aparición de los sofocos pudo


reducir a la mitad la frecuencia de esos síntomas durante los


tres meses que duró el ensayo, comparado con un grupo que no


recibió tratamiento alguno.


“Los resultados dicen que el enfoque daría resultado”, dijo


Kim Innes, de West Virginia University y que no participó del


estudio. “Fue un estudio sobre una muestra mediana que dio un


resultado promisorio, aunque no definitivo, sobre la efectividad


de la técnica utilizada”.


En una revisión de más de una docena de estudios previos


sobre la meditación, el yoga y el Tai Chi, Innes había observado


que esas técnicas podrían aliviar los síntomas de la menopausia,


pero que era muy pronto para confirmarlo.


Ahora, el equipo de Lotta Lindh-Åstrand, de la Universidad


de Linköping, analizó los efectos de un método de relajación


desarrollado en Suecia en los años 80 a partir de la terapia


cognitiva conductual.


Para eso, reunió a 60 mujeres suecas saludables: algo más de


la mitad realizó el método de relajación, mientras que el resto


no recibió tratamiento alguno (grupo control). La mayoría de las


participantes tenían más de 50, habían dejado de menstruar hacía


un año o más, pero todas sentían sofocos y sudoración nocturna.


Las 33 mujeres tratadas con relajación aprendieron a


concentrarse en la respiración y a liberar la tensión muscular


antes y durante los sofocos.


En la primera semana, las participantes registraron las


sensaciones antes y durante los sofocos u otros síntomas


menopáusicos. Luego, se las alentó a dedicar 15 minutos dos


veces por día a tensar y relajar los músculos de cabeza a pies.


De a poco, aprendieron a reducir el tiempo necesario para


relajarse con el control de la respiración y sin tensar los


músculos.


Al final del estudio, se les pidió que practicaran la


relajación 20 veces por día, durante 30 segundos cada vez. En el


ejercicio final, las mujeres debían poder aplicar esas


habilidades respiratorias y de relajación durante un sofoco.


Al inicio del estudio, todas las participantes tenían unos


10 sofocos por día. A los tres meses, según publica Menopause,


el grupo tratado con relajación padecía unos cuatro sofocos por


día, versus ocho sofoco el grupo control.


El equipo halló también una mejoría leve de la calidad de


vida, incluidos los trastornos del sueño y los dolores, en las


mujeres tratadas con relajación.


Para Innes y otros investigadores, el mecanismo detrás de


las terapias mente-cuerpo y sus efectos en los síntomas


menopáusicos podría estar asociado con el sistema nervioso


simpático, que controla la respuesta de “lucha y huída” y


funciones básicas como la frecuencia cardiaca, la presión y la


sudoración.


Por eso, el equipo señaló que los resultados no son finales


y que se necesitan más estudios.


“El próximo paso -dijo Innes- debería ser un estudio


aleatorizado” con un grupo control activo y entre, por ejemplo,


las técnicas de relajación y el ejercicio.


Lindh-Åstrand recordó que las técnicas de relajación no son


para todas las mujeres, en especial para aquellas con depresión


grave o ansiedad. Estas mujeres, paradójicamente, se sentirían


más tensas.


FUENTE: Menopause, 12 de noviembre del 2012.


Seniors/Aging News Headlines – Yahoo! News


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Duchess of Cambridge expecting a baby

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ABC News' Christina Ng and Carolyn Durand report:



Kate Middleton is pregnant.


The most eagerly awaited pregnancy was announced today by St. James Palace on behalf of Middleton and her husband Prince William.


The child, whether boy or girl, will eventually be heir to the British
throne according to new legislation awaiting final approval.



The duchess was admitted to King Edward VII Hospital today in central
London with hyperemesis gravidarum, an acute morning sickness which
requires supplementary hydration and nutrients, the palace said.

Click here for photos of Kate through the years.

"As the pregnancy is in its very early stages, Her Royal Highness is
expected to stay in hospital for several days and will require a period
of rest thereafter," the statement said.

The royal family was clearly delighted with the news.


"Their Royal Highnesses The Duke and Duchess of Cambridge are very
pleased to announce that The Duchess of Cambridge is expecting a baby,"
the palace said in a statement today. "The Queen, The Duke of Edinburgh,
The Prince of Wales, The Duchess of Cornwall and Prince Harry and
members of both families are delighted with the news."



The baby will be the queen's third great-grandchild.




Robert Lacey, author of the definitive book "Majesty" said, "The British
public and indeed the whole world will be delighted for the same, it
keeps the monarchy going. The royal wedding brought a magic back to the
monarchy and people are fascinated by William and Catherine."



The announcement follows relentless public and media speculation about
when Prince William and his wife would have an heir. The guessing game
began almost immediately after the couple said, "I do."

VOTE: What Should They Name the Baby?



Tabloids began snapping close-ups of Middleton's stomach for any
indication of a baby bump. Baby rumors abounded when the duchess held a
baby at a press event and when she declined peanut butter at another
event. British physicians are known to warn women against eating peanuts
during pregnancy. When the couple got a dog, Lupo, headlines wondered
if they were practicing for another addition to the family.



The palace, which rarely comments on speculation, took the unusual step
of saying, "We would be the ones to make the announcement, not
Hollywood."



"It is quite strange reading about it, but I try not to let it bother
me," Prince William said in an interview with ABC News' Katie Couric in
May 2012. "I'm just very keen to have a family and both Catherine and I
are looking forward to having a family in the future."



Asked by Couric if there was anything else he wanted to share, he coyly
answered, "You won't get anything out of me. Tight lipped."




Due to a dramatic change in the rules of succession, the royal couple's
first-born will likely be the heir to the throne, regardless of the
baby's gender.



Last year, the heads of 16 Commonwealth countries agreed to a change in
the rules of succession so that first-born children of either gender can
take the throne. Queen Elizabeth II was only eligible to be monarch
because her father had no male children. The British Parliament must
still amend existing law to make the succession change official.



"Put simply, if the Duke and Duchess of Cambridge were to have a little
girl, that girl would one day be our queen," British Prime Minister
David Cameron told reporters in 2011.



Royal babies have typically been born within one year of marriage.
Princess Diana gave birth to William just 11 months after her wedding
and the queen gave birth to Prince Charles six days before her first
wedding anniversary.

PHOTOS: Royal Heirs Around the World



Prince William and Kate were married on April 29, 2011.



Click here for an interactive look at William and Kate's love story.

William, who has long been known for making privacy a priority, will now
be faced with the inevitable fascination with his first child. And the
scrutiny will doubtless be familiar to him.




From his infant trip to Australia with his mother to his graduation from
St. Andrews University, William's life was filled with photo ops.



"We have a paradox here. William loathes the press and exposure to the
publicity. On the other hand, Diana exposed both sons at an early age.
They are immensely assured young men," Lacey said. "While he may want to
keep his children out the limelight, as a modern monarch he knows he
has to deal with the media."

PHOTOS: William and Kate: The College Years



Now, the name guessing game begins.



"They'll stick to traditional names," Lacey predicts. "William has a
great sense of history from working with his grandmother. The queen
would have him over for tea to teach him about history and the workings
of the monarchy."



It's typical for royals to have three or four names. Prince William's full name is William Arthur Philip Louis.



"If it's a girl it's not likely to be called Diana," Lacey said. "But
you're very likely to see Diana in one of the middle names. You might
very likely get Elizabeth Diana something. It shows the bravery with
which he's kept his mother's memory alive, right down to the ring on
Kate's finger."

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